{"title":"Other Enzymes","description":"\u003cp\u003eOther enzymes refer to a broad category of proteins that catalyze various biochemical reactions in cells, excluding well-defined groups such as kinases or proteases. These enzymes participate in diverse processes including metabolism, DNA replication, repair, and signalling. Studying these enzymes helps to understand cellular function and identify potential therapeutic targets.\u003c\/p\u003e","products":[{"product_id":"hguanylatekinase-his-tag","title":"hGuanylatekinase, His-Tag","description":"\u003cp\u003eThe transformation process of cellular guanosine monophosphate kinase (GMP) into guanosine monophosphate kinase (GDP) is performing due to human guanylate kinase which catalyses the phosphorylation reaction. Moreover, human guanylate kinase is known to have a similar structure to the A57R protein. In addition to phosphorylation catalysis, the enzyme plays a crucial role in the breakdown and synthesis of purines. Purine metabolism is present in a broad range of different organisms.\u003c\/p\u003e\n\u003ch6\u003e\n\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003e\n\u003c\/h6\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProduct Name:\u003c\/strong\u003e hGuanylatekinase, His-Tag\u003cbr data-mce-fragment=\"1\"\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCatalog No.:\u003c\/strong\u003e P2020-107\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRefSeq Links:\u003c\/strong\u003e UniProt: Q16774\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynonyms:\u003c\/strong\u003e guanosine monophosphate kinase; GMK; GMPK; Guanylate kinase; GUK1; hGMPK; human Guanylate kinase; GMP Kinase\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eSequence Information\u003c\/h6\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies:\u003c\/strong\u003e\u003cspan\u003e Homo sapiens, human\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTags:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003eHis-Tag, N-terminal\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence without tags \u003c\/strong\u003e\u003cspan\u003e\u003cem data-mce-fragment=\"1\"\u003e(AA 1-198)\u003c\/em\u003e\u003cstrong data-mce-fragment=\"1\"\u003e:\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/strong\u003eMSGPRPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFVTREV\u003cbr data-mce-fragment=\"1\"\u003eMQRDIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYI\u003cbr data-mce-fragment=\"1\"\u003eSVQPPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPGLFDVVIINDSLDQAYAE\u003cbr data-mce-fragment=\"1\"\u003eLKEALSEEIKKAQRTGA\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eProduct Information\u003c\/h6\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression Host:\u003c\/strong\u003e human, HEK293\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e PBS, pH 7,4\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Liquid, stored and shipped at -80°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt; 95% as determined by SDS-PAGE\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eBackground Information\u003c\/h6\u003e\n\u003cp\u003eHuman Guanylate kinase is the only known enzyme which catalyzes the ATP-dependent phosphorylation of cellular guanosine monophosphate (GMP) into guanosine diphosphate (GDP). Process is crucial for GMP and cyclic guanosine monophosphate (cGMP) recycling, essential for cellular viability and proliferation. It occurs in low eukaryotes, prokaryotes as well as in vertebrates. Human Guanylate kinase is a monomeric protein that is highly conserved and made up of approximately 200 amino acids. This enzyme belongs to the family of transferases with a phosphate group as phosphotransferases. The hGuanylatekinase is essential for producing the nucleotide building blocks of DNA, RNA. That enzyme is indispendable in metabolic activation of antiviral prodrugs. The hGuanylatekinase structure consists of three particular domains that are dynamic: LID, GMP-binding, and CORE domain.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ctable border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: left;\" data-mce-style=\"text-align: left;\"\u003e\n\u003cp\u003e\u003cstrong\u003eSDS-PAGE\/Coll. Coomassie\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"text-align: left;\" data-mce-style=\"text-align: left;\"\u003e\n\u003cp\u003e\u003cstrong\u003eHistogram of marked lane in gel picture\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 404px;\" data-mce-style=\"width: 404px;\"\u003e\u003ca title=\"SDS-PAGE\/Coll. Coomassie\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/hGuanylatkinase_P2020-107_SDS.png?v=1628089042\" target=\"_blank\"\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/hGuanylatkinase_P2020-107_SDS_480x480.png?v=1628089042\" alt=\"SDS-PAGE of hACE2-non-biotinylated\" style=\"margin-bottom: 16px; float: none;\"\u003e\u003c\/div\u003e\n\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 403px;\" data-mce-style=\"width: 403px;\"\u003e\u003ca title=\"Histogram of marked lane in gel picture\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/hGuanylatkinase_Histogram.png?v=1628089041\" target=\"_blank\"\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/hGuanylatkinase_Histogram_480x480.png?v=1628089041\" alt=\"Histogram (of marked lane in gel picture) hACE2-non-biotinylated\" style=\"margin-bottom: 16px; float: none;\"\u003e\u003c\/div\u003e\n\u003c\/a\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch6\u003eDownload\u003c\/h6\u003e\n\u003cp\u003e\u003ca title=\"Download Product Information for hGuanylatekinase, His-Tag\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/P2020-107_hGuanylatkinase_His-tag.pdf?v=1659336397\" target=\"_blank\"\u003eDownload Product Information for hGuanylatekinase, His-Tag\u003c\/a\u003e\u003c\/p\u003e","brand":"trenzyme","offers":[{"title":"100µg","offer_id":41033683566762,"sku":"P2020-107_100","price":330.0,"currency_code":"EUR","in_stock":true},{"title":"1mg","offer_id":41172970569898,"sku":"P2020-107_1000","price":2490.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/products\/hGuanylatkinase_structural-model.png?v=1629190655"},{"product_id":"psimp-glycosidase","title":"PsiMP glycosidase","description":"\u003cp\u003eThe PsiMP glycosidase biologically has a cleavage function and catalyzes the reversible cleavage of the C-C glycoside bond to form ribose-5-phosphate and uracil. PsiMP glycosidase, together with the enzyme pseudouridine kinase, is responsible for the degradation of pseudouridine in E. coli.\u003c\/p\u003e\n\u003ch6\u003e\n\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003e\n\u003c\/h6\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProduct Name:\u003c\/strong\u003e PsiMP glycosidase\u003cbr data-mce-fragment=\"1\"\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCatalog No.:\u003c\/strong\u003e P2020-109\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRefSeq Links:\u003c\/strong\u003e UniProt: P33025\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynonyms:\u003c\/strong\u003e Pseudouridine 5’-phosphate glycosidase; PsiMP glycosidase\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eSequence Information\u003c\/h6\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies:\u003c\/strong\u003e\u003cspan\u003e Escherichia coli; Salmonella sp. HNK130\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTags:\u003c\/strong\u003e\u003cspan\u003e His-Tag, N-terminal\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence without tags \u003c\/strong\u003e\u003cspan\u003e\u003cem data-mce-fragment=\"1\"\u003e(AA 1-312)\u003c\/em\u003e\u003cstrong data-mce-fragment=\"1\"\u003e:\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/strong\u003eMSELKISPELLQISPEVQDALKNKKPVVALESTIISHGMPF\u003cbr data-mce-fragment=\"1\"\u003ePQNAQTAIEVEETIRKQGAVPATIAIIGGVMKVGLSKEEIELLGREGHNVTKVSRRDLPF\u003cbr data-mce-fragment=\"1\"\u003eVVAAGKNGATTVASTMIIAALAGIKVFATGGIGGVHRGAEHTFDISADLQELANTNVTVV\u003cbr data-mce-fragment=\"1\"\u003eCAGAKSILDLGLTTEYLETFGVPLIGYQTKALPAFFCRTSPFDVSIRLDSASEIARAMVV\u003cbr data-mce-fragment=\"1\"\u003eKWQSGLNGGLVVANPIPEQFAMPEHTINAAIDQAVAEAEAQGVIGKESTPFLLARVAELT\u003cbr data-mce-fragment=\"1\"\u003eGGDSLKSNIQLVFNNAILASEIAKEYQRLAG\u003cbr\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eProduct Information\u003c\/h6\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression Host:\u003c\/strong\u003e \u003cem data-mce-fragment=\"1\"\u003eE. coli\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e PBS, pH 7,4\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Liquid, stored and shipped at -80°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt; 95% as determined by SDS-PAGE\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eBackground Information\u003c\/h6\u003e\n\u003cp\u003eThe enzymes PsiMP glycosidase and pseudouridine kinase are encoded by separate genes in bacterial genomes. PsiMP glycosidase is encoded by the yeiN gene, and pseudouridine kinase is encoded by the yeiC gene. Both genes belong to the same operon. In humans and other higher organisms, pseudouridine kinase and PsiMP glycosidase are not found. However, they are present in some eukaryotes as the only bifunctional enzymes.\u003cbr data-mce-fragment=\"1\"\u003eIn the process of pseudouridine degradation, when pseudouridine kinase phosphorylates pseudouridine, pseudouridine 5'-phosphate (PsiMP) is formed as a degradation product of RNAs. PsiMP is a non-classical nucleoside that has a glycosidic C-C bond and is present in human urine.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ctable border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: left;\" data-mce-style=\"text-align: left;\"\u003e\n\u003cp\u003e\u003cstrong\u003eSDS-PAGE\/Coll. Coomassie\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"text-align: left;\" data-mce-style=\"text-align: left;\"\u003e\n\u003cp\u003e\u003cstrong\u003eHistogram of marked lane in gel picture\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 404px;\" data-mce-style=\"width: 404px;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/PsiMP-glycosidase_P2020-109_SDS_065ce276-3296-4c2e-bdd5-322fd0913df3.png?v=1636625692\" title=\"SDS-PAGE\/Coll. Coomassie\" rel=\"noopener noreferrer\" target=\"_blank\"\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"SDS-PAGE of PsiMP glycosidase\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/PsiMP-glycosidase_P2020-109_SDS_065ce276-3296-4c2e-bdd5-322fd0913df3_480x480.png?v=1636625692\"\u003e\u003c\/div\u003e\n\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 403px;\" data-mce-style=\"width: 403px;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/PsiMP-glycosidase_Histogram.png?v=1635166634\" title=\"Histogram of marked lane in gel picture\" rel=\"noopener noreferrer\" target=\"_blank\"\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"Histogram (of marked lane in gel picture) PsiMP glycosidase\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/PsiMP-glycosidase_Histogram_480x480.png?v=1635166634\"\u003e\u003c\/div\u003e\n\u003c\/a\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch6\u003eDownload\u003c\/h6\u003e\n\u003cp\u003e\u003ca title=\"Download Product Information for PsiMP glycosidase\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/P2020-109_PsiMP_glycosidase_cb6ca9b9-a04a-444c-81a8-35112ee2a1df.pdf?v=1647335111\" target=\"_blank\"\u003eDownload Product Information for PsiMP glycosidase\u003c\/a\u003e\u003c\/p\u003e","brand":"trenzyme","offers":[{"title":"100µg","offer_id":41630852677802,"sku":"P2020-109_100","price":790.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/products\/P2020-109_PsiMP-glycosidase.png?v=1635166813"},{"product_id":"catalase","title":"Catalase","description":"\u003cp\u003eCatalase (KatA) from Helicobacter pylori is an enzyme used as biomarker for diagnostic of duodenal ulcer (DU).\u003c\/p\u003e\n\u003ch6\u003e\n\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003e\n\u003c\/h6\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProduct Name:\u003c\/strong\u003e Catalase\u003cbr data-mce-fragment=\"1\"\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCatalog No.:\u003c\/strong\u003e P2020-127\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRefSeq Links:\u003c\/strong\u003e UniProt: P77872; NP_207669.1; NC_000915.1; WP_000247370.1;, NC_018939.1; PDB: 1QWL; 2IQF\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynonyms:\u003c\/strong\u003e KatA\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eSequence Information\u003c\/h6\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies:\u003c\/strong\u003e\u003cspan\u003e Helicobacter pylori\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTags:\u003c\/strong\u003e\u003cspan\u003e GFP\/His-Tag, C-terminal\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence without tags \u003c\/strong\u003e\u003cspan\u003e\u003cspan\u003e\u003cem data-mce-fragment=\"1\"\u003e(AA 1-505)\u003c\/em\u003e\u003cstrong data-mce-fragment=\"1\"\u003e:\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/span\u003e\n\u003cp\u003eMVNKDVKQTTAFGAPVWDDNNVITAGPRGPVLLQSTWFLEKLAAFDRERIPERVVHAKGS\u003cbr\u003eGAYGTFTVTKDITKYTKAKIFSKVGKKTECFFRFSTVAGERGSADAVRDPRGFAMKYYTE\u003cbr\u003eEGNWDLVGNNTPVFFIRDAIKFPDFIHTQKRDPQTNLPNHDMVWDFWSNVPESLYQVTWV\u003cbr\u003eMSDRGIPKSFRHMDGFGSHTFSLINAKGERFWVKFHFHTMQGVKHLTNEEAAEVRKYDPD\u003cbr\u003eSNQRDLFNAIARGDFPKWKLSIQVMPEEDAKKYRFHPFDVTKIWYLQDYPLMEVGIVELN\u003cbr\u003eKNPENYFAEVEQAAFSPANVVPGIGYSPDRMLQGRLFSYGDTHRYRLGVNYPQIPVNKPR\u003cbr\u003eCPFHSSSRDGYMQNGYYGSLQNYTPSSLPGYKEDKSARDPKFNLAHIEKEFEVWNWDYRA\u003cbr\u003eDDSDYYTQPGDYYRSLPADEKERLHDTIGESLAHVTHKEIVDKQLEHFKKADPKYAEGVK\u003cbr\u003eKALEKHQKMMKDMHGKDMHHTKKKK\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eProduct Information\u003c\/h6\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression Host:\u003c\/strong\u003e \u003cem\u003eE. coli\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation: \u003c\/strong\u003ePBS; pH 7.4.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Liquid, stored and shipped at -80°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt; 75% as determined by SDS-PAGE\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eBackground Information\u003c\/h6\u003e\n\u003cp\u003eCatalases are conserved and abundant enzymes found in all domains of life. They protect against oxidative stress and are highly expressed. In the gastric pathogen Helicobacter pylori, KatA levels are estimated to be up to 4-5% of the total protein content. The presence of the enzyme is ubiquitous, it could be detected in the cytoplasm, the periplasm and on the cell surface as well as being readily detected extracellularly. The enzyme is described to use heme as cofactor.\u003cbr\u003eKatA is used as biomarker for duodenal ulcer (DU) and also for gastritic cancer (GC).\u003c\/p\u003e\n\u003ctable border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: left;\" data-mce-style=\"text-align: left;\"\u003e\n\u003cp\u003e\u003cstrong\u003eSDS-PAGE\/Coll. Coomassie\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"text-align: left;\" data-mce-style=\"text-align: left;\"\u003e\n\u003cp\u003e\u003cstrong\u003eHistogram of marked lane in gel picture\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 404px;\" data-mce-style=\"width: 404px;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/Catalase_P2020-127_SDS.png?v=1649344396\" title=\"SDS-PAGE\/Coll. Coomassie\" rel=\"noopener noreferrer\" target=\"_blank\"\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"SDS-PAGE of Catalase\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/Catalase_P2020-127_SDS_480x480.png?v=1649344396\"\u003e\u003c\/div\u003e\n\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 403px;\" data-mce-style=\"width: 403px;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/Catalase_P2020-127_Histogram.png?v=1649344395\" title=\"Histogram of marked lane in gel picture\" rel=\"noopener noreferrer\" target=\"_blank\"\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"Histogram (of marked lane in gel picture) Catalase\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/Catalase_P2020-127_Histogram_480x480.png?v=1649344395\"\u003e\u003c\/div\u003e\n\u003c\/a\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch6\u003eDownload\u003c\/h6\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/P2020-127_Catalase.pdf?v=1659337054\" title=\"Download Product Information for Catalase\" target=\"_blank\"\u003eDownload Product Information for Catalase\u003c\/a\u003e\u003c\/p\u003e","brand":"trenzyme","offers":[{"title":"100µg","offer_id":42798883438762,"sku":"P2020-127_100","price":899.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/products\/Catalase_structural-model.png?v=1649344605"},{"product_id":"alpha-1-antitrypsin","title":"Alpha-1-antitrypsin","description":"\u003cp\u003eRecombinant Alpha-1-antitrypsin or also known as Alpha-1-proteinase inhibitor is an inhibitor of serine proteases (Serpin). Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator.\u003cbr\u003eThe protein was produced using a mammalian cell system (HEK) and contains a His-Tag.\u003c\/p\u003e\n\u003ch6\u003e\n\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003e\n\u003c\/h6\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProduct Name:\u003c\/strong\u003e Alpha-1-antitrypsin\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCatalog No.:\u003c\/strong\u003e P2020-112\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRefSeq Links:\u003c\/strong\u003e UniProt: P01009; NP_000286.3; NM_000295.4; PIR: A21853; GeneID: 5265\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynonyms:\u003c\/strong\u003e Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1; A1AT Protein; Alfa1 antitrypsin; Alpha 1-antitrypsin; Alpha 1-Proteinase Inhibitor; Alpha 1-proteinase inhibitor (human); Alpha 1-proteinase inhibitor, human; Alpha-1 protease inhibitor; Alpha-1 proteinase inhibitor (human); Alpha-1-antiproteinase; Alpha-1-antitrypsin; Alpha-1-proteinase Inhibitor (human); Alpha-1-proteinase inhibitor human; Alpha-1-proteinase Inhibitor, Human; Alpha-1-proteinase inhibitor, human; Alpha1-proteinase Inhibitor; Alpha1-proteinase inhibitor (human); alpha1-proteinase inhibitor human; API\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eSequence Information\u003c\/h6\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies:\u003c\/strong\u003e\u003cspan\u003e Homo sapiens\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTags: \u003c\/strong\u003e\u003cspan\u003eHis-tag, N-terminal\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence without tags \u003c\/strong\u003e\u003cspan\u003e\u003cem\u003e(AA 25-418)\u003c\/em\u003e\u003cstrong data-mce-fragment=\"\"\u003e:\u003cbr data-mce-fragment=\"\"\u003e\u003c\/strong\u003eEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATA\u003cbr\u003eFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFL\u003cbr\u003eSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDT\u003cbr\u003eVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVL\u003cbr\u003eLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLK\u003cbr\u003eSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI\u003cbr\u003ePPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQK\u003cbr data-mce-fragment=\"\"\u003e\u003cbr\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eProduct Information\u003c\/h6\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression Host:\u003c\/strong\u003e human, HEK293\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e 10 mM Tris, 200 mM NaCl, 1 mM EDTA, 1 mM ß-Mercaptoethanol; pH 8.0\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Liquid, stored and shipped at -80°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e 95% as determined by SDS-PAGE\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eBackground Information\u003c\/h6\u003e\n\u003cp\u003eAlpha-1-antitrypsin also known as Alpha-1 proteinase inhibitor is a serine protease inhibitor (Serpin). Its primary mechanism is inhibiting the action of the serine protease called elastase (also plasmin and thrombin) preventing the proteolysis of elastin tissues in alveolar lung structures. The reactive center loop (RCL) of alpha-1 proteinase inhibitor extends out from the body of the protein and directs binding to the target protease. The protease cleaves the serpin at the reactive site, establishing a covalent linkage between the carboxyl group of the serpin reactive site and the serine hydroxyl of the protease. The resulting inactive serpin-protease complex is highly stable.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ctable border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: left;\" data-mce-style=\"text-align: left;\"\u003e\n\u003cp\u003e\u003cstrong\u003eSDS-PAGE\/Coll. Coomassie\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"text-align: left;\" data-mce-style=\"text-align: left;\"\u003e\n\u003cp\u003e\u003cstrong\u003eHistogram of marked lane in gel picture\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 404px;\" data-mce-style=\"width: 404px;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/Alpha-1-antitrypsin_P2020-112_SDS.png?v=1644315397\" title=\"SDS-PAGE\/Coll. Coomassie\" rel=\"noopener noreferrer\" target=\"_blank\"\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"SDS-Page Alpha-1-antitrypsin\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/Alpha-1-antitrypsin_P2020-112_SDS_480x480.png?v=1644315397\"\u003e\u003c\/div\u003e\n\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 403px;\" data-mce-style=\"width: 403px;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/Alpha-1-antitrypsin_Histogram.png?v=1644315397\" title=\"Histogram of marked lane in gel picture\" rel=\"noopener noreferrer\" target=\"_blank\"\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"Histogram Alpha-1-antitrypsin\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/Alpha-1-antitrypsin_Histogram_480x480.png?v=1644315397\"\u003e\u003c\/div\u003e\n\u003c\/a\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch6\u003eDownload\u003c\/h6\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/P2020-112_Alpha-1-antitrypsin.pdf?v=1679586779\" title=\"Download Product Information for Alpha-1-antitrypsin\" target=\"_blank\"\u003eDownload Product Information for Alpha-1-antitrypsin\u003c\/a\u003e\u003c\/p\u003e","brand":"trenzyme","offers":[{"title":"100µg","offer_id":44464657531147,"sku":"P2020-112_100","price":490.0,"currency_code":"EUR","in_stock":true},{"title":"1mg","offer_id":44464657563915,"sku":"P2020-112_1000","price":1190.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0530\/3055\/1722\/files\/Alpha_1_antitrypsin_structural-model_ef4b97c4-f363-4321-ac61-b942d213e228.png?v=1689064846"}],"url":"https:\/\/shop.trenzyme.com\/collections\/other-enzymes\/formulation_liquid-pbs+species_escherichia-coli+purity_-95.oembed","provider":"shop.trenzyme.com","version":"1.0","type":"link"}