HER2/ErbB2

€350.00

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SKU: P2020-165_100 trenzyme

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Description

Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, is a receptor tyrosine kinase that plays a crucial role in regulating cell growth, proliferation and survival. Additionally, HER2 signaling promotes cell migration, adhesion and invasion, essential for normal tissue development and wound healing. However, dysregulation of HER2 signaling, due to gene amplification or overexpression, leads to uncontrolled cell growth, tumor formation, and metastasis. Therefore, HER2 has emerged as an important therapeutic target in various cancer types, especially in breast cancer, where HER2-targeted therapies have significantly improved treatment outcomes.

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