B7-H3

B7-H3 (CD276) is an immune checkpoint protein belonging to the B7 family of co-stimulatory and co-inhibitory molecules. It is expressed on various immune cells and many types of solid tumors. While its precise function in immune regulation remains complex and context-dependent, B7-H3 is generally associated with immune evasion in cancer, making it a promising target for cancer immunotherapy and diagnostic applications.