Lanmodulin (LanM)


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SKU: P2020-126 trenzyme

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Lanmodulin (LanM) is a bacterial protein exhibiting metal-binding properties. It binds rare-earth elements (REEs) with very high affinity.


  • Product Name: LanM
  • Catalog No.: P2020-126
  • RefSeq Links: UniProt: B1ZIE8; WP_003601797.1; PDB: 6MI5_X
  • Synonyms: Lanmodulin; Lanthanides; Lns
Cellebrity Kolben Cell Cartoon trenzyme

Sequence Information

  • Species: Methylorubrum extorquens
  • Tags: His-Tag, C-terminal
  • Sequence without tags (AA 1-133):


Product Information

  • Expression Host: E. coli
  • Formulation: PBS; pH 7.4.
  • Format: Liquid, stored and shipped at -80°C
  • Purity: > 95% as determined by SDS-PAGE

Background Information

Lanthanides (Lns) are essential cofactors in certain enzymes. Lanmodulin (LanM) is a metal binding protein found in several lanthanide-utilizing, methylotrophic bacteria like Methylorubrum sp. The protein exhibits unique metal-binding properties and binds rare-earth elements (REEs) with very high affinity, often better than many synthetic chelators. LanM-REE complexes are stable at extreme conditions like high temperature, repeated acid treatments down to pH 2.5 and up to molar amounts of competing non-REE metal ions.
Therefore, lanmodulin could be used even in harsh chemical processes for selective recovery of a broad range of REE from precumbustion coal and electronic waste leachates.

SDS-PAGE/Coll. Coomassie

Histogram of marked lane in gel picture

SDS-PAGE of lanM
Histogram (of marked lane in gel picture) of lanM

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