![Structural model of SARS-CoV-2 S1 (RBD) B.1.141/B.1.258 (Scotland/U.K.)](http://shop.trenzyme.com/cdn/shop/products/NEW_s1-protein_mutation_structural-model_N439K_{width}x.png?v=1634740608)
SARS-CoV-2 S1 (RBD) B.1.141/B.1.258 (Scotland/U.K.)
€420.00 €470.00
Price excl. shipping costs excl. VAT. For more information, see our shipping policy
SKU: P2020-034 trenzyme
Description
Recombinant protein of the receptor binding domain (RBD), Mutant (N439K) of SARS-CoV-2 (COVID-2019) Spike S1 from Wuhan pneumonia virus with C-terminal His-Tag. The N439K mutation, lineage B.1.141/B.1.258 (Scotland/UK), is known as the second common mutation in the RBD of SARS-CoV-2 and binds with high affinity to human ACE2 receptor. The mutation may result in immune escape from a panel of neutralizing monoclonal antibodies and polyclonal sera of persons recovered from infection.
![](http://shop.trenzyme.com/cdn/shop/files/Cellebrity_Kolben_left_ad7b1e6b-d456-415f-ad87-8b4f269911e7.png?v=1712041845)