SARS-CoV-2 S1 (RBD) Epsilon, B.1.427/B.1.429 (California/USA), GFP/His-Tag

€420.00 €470.00

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SKU: P2020-048 trenzyme

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Recombinant protein of the receptor binding domain (RBD), Mutant (L452R) of SARS-CoV-2 (COVID-2019) Spike S1 from Wuhan pneumonia virus with C-terminal GFP/His-Tag. The mutation L452R is characteristic for the SARS-CoV-2 virus variants B.1.427 or B.1.429 emerged in California/USA. These variants are also known as CAL.20C. The mutation is affecting the receptor binding domain (RBD) of the spike protein, which the virus uses to bind to human cells receptors and enter them. Due to the mutation, the virus is allowed to bind with higher affinity to human ACE2 receptor, which results in increased transmissibility of the SARS-CoV-2 virus.

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