mature TGF-beta 1


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SKU: P2020-116 trenzyme

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Transforming growth factor-beta 1 (TGF-β1) is a pleiotropic cytokine involved in a myriad of cellular functions, including cell growth, differentiation, immune regulation and tissue homeostasis. It is a member of the TGF-β superfamily and exerts its effects by binding to specific cell surface receptors, thereby activating intracellular signaling pathways that mediate regulatory signals, controlling expression of target genes. Dysregulation of TGF-β1 is implicated in numerous diseases, such as cancer, fibrosis, and autoimmune disorders. Understanding the complex functions and regulatory mechanisms of TGF-β1 is essential for developing therapeutic strategies targeting its pathways and mitigating associated pathological conditions.

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